Thursday, April 3, 2014

Eosinophils in the dermis

Eosinophils in the dermis                 See DX Path for details of the conditions below

Large numbers in the dermis suggest arthropod bite including scabies, pre bullous pemphigoid and Well's syndrome or eosinophilic cellulitis.

Some increase is also seen in drug reactions, urticaria and so called deep dermal hypersensitivity reactions. Flame figures are orange deposits of eosinophilic basic protein seen in the dermis particularly in Well's syndrome
Arthropod bites
Parasitic diseases
Drug eruptions
Wells syndrome
Granuloma faciale
Urticaria
Urticarial pemphigoid
Churg-Strauss syndrome
Angiolymphoid hyperplasia with eosinophilia (histiocytoid hemangioma)
Accompanying some examples of anaplastic large cell lymphoma

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